Regulatory Properties of AMP Deaminase Isozymes
AMP deaminase catalyzes the deamination of AMP to form IMP and ammonia. The function of AMP deaminase in cellular metaholism remains obscure, but a number of physiological roles have been proposed. The enzyme may be responsible for the conversion of adenine nucleotide to inosine or guanine nucleotide1, for stabilizing the adenylate energy charge2, and the reaction of the purine nucleotide cycle3.
KeywordsMonovalent Cation Energy Charge Adenylate Kinase Adenylate Energy Charge Isozyme Band
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- 3.J. M. Lowenstein, Ammonia production in muscle and other tissues: The purine nucleotide cycle, Physiol. Rev., 52:382 (1972).Google Scholar