Adenosine Deaminase Conversion Proteins: A Potential Role

  • Paul P. Trotta
  • M. Earl Balis
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)


Adenosine deaminase (ADase) catalyzes the deamination of adenosine. Its importance is underscored by clinical and in vitro evidence that supports a causal relationship between absence of ADase and one form of severe combined immunodeficiency disease (1). In addition, the metabolism of several anti-tumor and anti-viral nucleosides is regulated by this enzyme (2).


Adenosine Deaminase Severe Combine Immunodeficiency Disease Conversion Activity Adenosine Deaminase Activity Erythrocyte Plasma Membrane 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Paul P. Trotta
    • 1
  • M. Earl Balis
    • 1
  1. 1.Sloan-Kettering Institute for Cancer ResearchNew YorkUSA

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