Role of Human Hypoxanthine Guanine Phosphoribosyltransferase in Nucleotide Interconversion

  • Alessandro Giacomello
  • Costantino Salerno
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)


It is well established that human Hypoxanthine-Guanine Phospho-ribosyltransferase (HGPRT, EC catalyzes the reactions:


Xanthine Oxidase Steady State Kinetic Hypoxanthine Guanine Phosphoribosyltransferase Irreversible Step Lesch Nyhan Syndrome 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Alessandro Giacomello
    • 1
  • Costantino Salerno
    • 1
  1. 1.Istituti di Reumatologia e di Chimica BiologicaUniversità di Roma e Centro di Biologia Molecolare del C.N.R.RomaItalia

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