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Regulation of Purine Savage Enzymes in E. coli

  • Roy A. Levine
  • Milton W. Taylor
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)

Abstract

There is no doubt that in eukaryotic cells there is an interplay between the de novo purine biosynthetic pathway and purine salvage enzymes, or products of these enzymes. Feedback inhibition of the first specific enzyme of the pathway, PRPP amidotransferase, occurs via AMP or GMP and repression of the pathway is possibly controlled by the product of the salvage enzymes, APRT and HGPRT (Henderson, 1972).

Keywords

Adenosine Deaminase Purine Metabolism Purine Base Purine Biosynthesis Fold Stimulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Henderson, J.F., 1972, Regulations of purine biosynthesis, ACS Monograph, 170, Washington, D.C.Google Scholar
  2. Hochstadt-Ozer, J. and Stadtman, E.R., 1971, J. Biol. Chem., 240: 5294–5303.Google Scholar
  3. Nygaard, P., 1976, Purine Metabolism in Man, Advance in Experimental Medicine and Biology, 76A: 186–195.Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Roy A. Levine
    • 1
  • Milton W. Taylor
    • 1
  1. 1.Department of BiologyIndiana UniversityBloomingtonUSA

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