Purine Salvage Enzymes in Man and Leishmania donovani
A comparison of the enzymes of pathogenic protozoa to those of man is of fundamental importance to the search for much needed chemotherapeutic agents. The enzymes involved in purine salvage are of particular interest because most pathogenic protozoa lack the ability to synthesize purines de novo and consequently are obligate salvagers of preformed purines.
KeywordsThymidine Kinase Adenosine Deaminase Purine Nucleoside Aldehyde Oxidase Purine Nucleoside Phosphorylase
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