Towards Selective Laser Photochemistry of Biomolecules
Modern lasers make it possible to change such radiation parameters as the frequency, intensity, and duration of pulses over a wide range. This has made possible investigations on the selective action of laser radiation on substance. Selective action means an action on certain atoms or molecules, mixed with others that are similar but not identical. The rest of the atoms or molecules either are not influenced at all or are acted upon in lesser degree. The research in this newest branch of quantum electronics is being widely performed all over the world. Laser isotope separation can be indicated as the most exciting among these investigations. It would be interesting to apply the idea of selective laser action to nucleic acid molecules. As is well known, these polymers, which are exceptionally important from the biological point of view, consist of five bases: guanine (G), cytosine (C), thymine (T), adenine (A) and uracil (U). The task in this case is to induce physical (excitation, ion formation) and/or chemical (breaking of bonds, chemical reaction) changes in the bases of one type by acting with laser radiation on a nucleic acid molecule. But the bases of other types herein remain essentially unchanged.
KeywordsDifference Spectrum Selective Action Ultrashort Pulse Acid Aqueous Solution Nucleic Acid Molecule
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