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Control of Mitochondrial Respiration by the Protonmotive Force

  • K. van Dam
  • H. Woelders
  • A. M. A. F. Colen

Abstract

Since the development of the chemiosmotic hypothesis by Mitchell (1) a central role in energy conservation has been attributed to protons (2). The experiments, designed to verify this role, have been very successful in demonstrating that movement of protons generally accompanies the process of energy transduction in mitochondria, chloroplasts and bacteria. However, up to this moment, there are a number of observations that are difficult to reconcile with the original scheme proposed by Mitchell. A discussion of these anomalies can be found in a review by Westerhoff et al. (3).

Keywords

Respiratory Chain Original Scheme Energy Transduction Bulk Aqueous Phase Experimental Argument 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • K. van Dam
    • 1
  • H. Woelders
    • 1
  • A. M. A. F. Colen
    • 1
  1. 1.Laboratory of BiochemistryUniversity of AmsterdamAmsterdamThe Netherlands

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