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The Effects of a Magnetic Field on DNA Synthesis by Ascites Sarcoma 37 Cells

  • Leo D’Souza
  • Vernon R. Reno
  • Leo G. Nutini
  • Elton S. Cook

Abstract

Barnothy has reported that exposure to a magnetic field increased the rejection of tumor transplants in mice and increased the life-span.(1) Gross found that magnetic pretreatment of tumor-bearing mice increased the average life-span, but the increase was not statistically significant.(2) Since any in vivo effects may be indirect, in vitro findings are of interest. Mulay and Mulay found increased degeneration of ascites Sarcoma 37 cells (but not of the solid tumor) exposed to higher intensity magnetic fields (4400 to 8000 Oe).(3,4) Butler and Dean reported that the growth of KB cells in tissue culture was inhibited by a 4000-Oe field.(5) On the other hand, Hall et al.(6) found no lethal effects of 5000-Oe or 77,000-Oe fields on HeLa cells, in agreement with negative results of a 1200-Oe field on the same cells reported by Halpern and Greene.(7) The same authors reported further negative results of fields from 0.0005 to 1200 Oe the growth of HeLa, KB, WI-38 as well as Chinese hamster and chick embryo cells(8)

Keywords

Magnetic Field Serratia Marcescens Tritiated Thymidine Tumor Cell Suspension Chick Embryo Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1969

Authors and Affiliations

  • Leo D’Souza
    • 1
  • Vernon R. Reno
    • 1
  • Leo G. Nutini
    • 1
  • Elton S. Cook
    • 1
  1. 1.Divisions of Chemistry and Biochemistry and of Biology and Experimental MedicineInstitutum Divi ThomaeCincinnatiUSA

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