The Differentiation of Multi-Infarct and Alzheimer Dementia

  • John Marshall


The great decline in mortality from infective disease in the Western industrialized countries as a result of the introduction of antibiotics has greatly changed the age structure of the population. About 14 per cent of people are now aged 65 years or more. They become heir to the diseases of later life among which is numbered dementia. It is estimated that about 1 in 20 of those aged 65 years or more will become demented; among those aged over 80 years — the old old of geriatrics — the figure is nearer to 1 in 5. Dementia is therefore a new type of epidemic, not in the sense of being passed from person to person but in the sense of large numbers being afflicted at any one time.


Cerebral Blood Flow Vascular Dementia Small Infarct Western Industrialize Country Acetyl Choline Transferase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    V.C. Hachinski, N.A. Lassen and J. Marshall, Multi-infarct dementia A cause of mental deterioration in the elderly, The Lancet 2: 207 (1974).CrossRefGoogle Scholar
  2. 2.
    V.C. Hachinski, L.D. Iliff, E. Zilkha, G.H. du Boulay, V.L. McAllister, J. Marshall, R.W. Ross Russell and L. Symon, Cerebral blood flow in dementia, Arch. Neurol. 32: 632 (1975).PubMedCrossRefGoogle Scholar
  3. 3.
    W.G. Rosen, R.D. Terry, P.A. Fuld, R. Katzman and A. Peck, Pathological verification of ischemic score in differentiation of dementias, Ann. Neurol. 7: 486 (1980).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • John Marshall
    • 1
  1. 1.Institute of NeurologyNational Hospital for Nervous Diseases Queen SquareLondonEngland

Personalised recommendations