Gaba-Ergic Treatment of Tardive Dyskinesia

  • K. Heinrich
  • J. Tegeler
  • W. Wöller
  • H. Quadbeck
  • G. Arendt
  • E. Klieser
  • H. Lange
  • E. Lehmann


While the exact pathophysiology of neuroleptic-induced tardive dyskinesia is still unknown, dopaminergic supersensitivity and a disturbed balance between the dopaminergic and cholinergic systems seem to play an important role in this disorder. GABA, which exerts an inhibitory influence on dopaminergic neurotransmission, is also supposed to be involved.


Tardive Dyskinesia Gaba Receptor Sodium Valproate Abnormal Involuntary Movement Scale Disturbed Balance 
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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • K. Heinrich
    • 1
  • J. Tegeler
    • 1
  • W. Wöller
    • 1
  • H. Quadbeck
    • 1
  • G. Arendt
    • 1
  • E. Klieser
    • 1
  • H. Lange
    • 1
  • E. Lehmann
    • 1
  1. 1.Psychiatrische KlinikUniversität DüsseldorfDüsseldorf 12Germany

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