Ten Years of Lithium Transport Research
The occasion of an international symposium on the subject of lithium transport appropriately calls for a short review of some of the history behind this area of research. We are fortunate to have represented in this symposium a number of researchers from Europe and the United States, all of whom have been working for several years in this particular area of biological psychiatry. The communication that symposiums such as this provide for those of us working in this area will hopefully accelerate progress in understanding the relevance of lithium transport to the clinical practice of psychiatry. But first, a short review of the last ten years of lithium transport research. This will be a personal view of things reflecting primarily those events which have most influenced my own research directions.
KeywordsLithium Level Major Affective Disorder Human RBCs Plasma Lithium Lithium Transport
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- 6.D. G. Ostrow, M. Trevisan, A. Okonek, R. Gibbons, R. Cooper, J. M. Davis, Sodium dependent membrane processes in major affective disorders, in: “Biological Markers in Psychiatry and Neurology,” I. Hanin and E. Usdin, eds., Pergamon Press, Oxford (1982).Google Scholar
- 8.D. G. Ostrow, G. N. Pandey, J. M. Davis, S. S. Chang, D. C. Tosteson, Clinical study of lithium transport: A defect of phloretin-sensitive lithium transport in bipolar illness, Proceedings of the 1977 American Psychiatric Association Annual Meeting 130:152–153.Google Scholar
- 9.D. G. Ostrow, A. Okonek, S. Sparks, S. Flagel, R. Cooper, J. M. Davis, RBC lithium efflux in major affective disorders, Proceedings of the 1982 American Psychiatric Association Annual Meeting 135:180.Google Scholar