Amphetamine Induced Arousal in Human Subjects as a Model for Mania

  • David Jacobs


One avenue for investigating the biological aspects of mania, is to use a pharmacological model and in the past a variety of animal models have been proposed. These experiments however risk being an over-simplification with the additional difficulty of extrapolation from one species to another. Furthermore, animal models allow no measure of the mental state, a necessity in research in the field of psychological illness.


Placebo Lithium Attenuation Dopamine Cortisol 


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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • David Jacobs
    • 1
  1. 1.Department of Postgraduate Education in Psychiatry UnitSelby CentreShenton ParkAustralia

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