Advertisement

Neuroendocrine and Receptor Binding Studies in Schizophrenia

  • M. Ackenheil
  • M. Albus
  • B. Bondy
  • F. Müller-Spahn
  • U. Münch
  • D. Naber

Abstract

Dopamine agonists such as L-DOPA and amphetamine have been found to exacerbate schizophrenia, while neuroleptics, dopamine (DA) antagonists, have antipsychotic effects. These results of many clinical studies sustain the DA hypothesis of schizophrenia.

Keywords

Schizophrenic Patient Growth Hormone Response Growth Hormone Stimulation Receptor Binding Study Chronic Schizophrenic Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    M. Ackenheil: Biochemical effects of apomorphine: contribution to schizophrenia research. In: Apomorphine and other dopaminergics. Vol. II Corsini GV, Gessa GL (eds) pp 215–225. Raven Press New York (1981)Google Scholar
  2. 2.
    J. Rotrosen, B.M. Angrist, S. Gershon, E.J. Sachar, F.S. Halpern: Neuroendocrine assessment of dopaminergic activity in schizo — phrenia. In: Advances in Biochemical Psychopharmacol. Vol. 16 Gessa GL, Costa E. (eds) pp 112–118. Raven Press New York (1977)Google Scholar
  3. 3.
    P. Ettigi, N.P.V. Nair, S. Lai, P. Cervantes, H. Guyda: Effect of apomorphine on growth hormone and prolactin secretion in schizophrenic patients, with or without oral dyskinesia, with — drawn from chronic neuroleptic therapy. J Neurol Neurosurg Psychiat 39:870–876 (1976)PubMedCrossRefGoogle Scholar
  4. 4.
    G. Pandey, D. Farver, C. Taminga, S. Ericksen, S. Ali, J.M. Davis: Postsynaptic supersensitivity in schizophrenia; Am J Psychiat 134:518–522 (1977)PubMedGoogle Scholar
  5. 5.
    S. Lai, G. Tolis, J.B. Martin, G.M. Brown, H. Juyela: Effect of Clonidine on growth hormone, prolactin, luteinizing hormone, follicle stimulating hormone, and thyroid-stimulating hormone in the serum of normal men. J Clin Endocrinol Metab 41:827–836 (1975)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • M. Ackenheil
    • 1
  • M. Albus
    • 1
  • B. Bondy
    • 1
  • F. Müller-Spahn
    • 1
  • U. Münch
    • 1
  • D. Naber
    • 1
  1. 1.Psychiatric Hospital of the University of MunichMunich 2Germany

Personalised recommendations