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Disturbances in Serine-Glycine Metabolism in Relation to Acute Psychoses with Psychedelic Symptoms

  • Jacques Bruinvels
  • Lolke Pepplinkhuizen

Abstract

Psychoses showing complete recovery mostly have an episodic course and belong to the large group of acute psychotic syndromes which cannot be classified either as schizophrenic, paranoid, organic mental or affective disorders.

Keywords

Biological Psychiatry Acute Intermittent Porphyria Episodic Psychosis Serine Hydroxymethyltransferase Recovered Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bruinvels, J., Pepplinkhuizen, L., van Tuijl, H.R., Moleman, P., and W. Blom, 1980, Role of serine, glycine, and the tetrahydrofolic acid cycle in schizoaffective psychosis. A hypothesis relating porphyrin biosynthesis and transmethylation, in: Enzymes and Neurotransmitters in Mental Disease, E. Usdin, T.L. Sourkes, and M.B.H. Youdim, eds., John Wiley & Sons Ltd., Chapter II.8.Google Scholar
  2. Meller, E., and Friedhoff, A.J., 1979, 5-Methyltetrahydrofolate and metabolism of biogenic amines, in: Folic Acid in Neurology, Psychiatry and Internal Medicine, M.I. Botez and E.H. Reynold, eds., Raven Press, New York, p.157.Google Scholar
  3. Pearson, A.G., and Turner, A.J., 1979, The formation of β-carboline alkaloids mediated by serine hydroxymethyltransferase, FEBS Letters 1: 96.CrossRefGoogle Scholar
  4. Pepplinkhuizen, L., Bruinvels, J., Blom, W., and Moleman, P, 1980, Schizophrenia-like psychosis caused by a metabolic disorder, The Lancet, March 1: 454.CrossRefGoogle Scholar
  5. Stein, J.A., and P. Tschudy, 1970, Acute intermittent porphyria, a clinical and biochemical study of 46 patients, Medicine, Baltimore 49: 1.Google Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Jacques Bruinvels
    • 1
  • Lolke Pepplinkhuizen
    • 1
  1. 1.Group Biological PsychiatryMedical Faculty Erasmus University RotterdamDR RotterdamThe Netherlands

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