The Significance of Psychopathological Classification in Interpreting Biochemical Findings

  • Eberhard Gabriel


The empirical background of my contribution is a research programme in schizophrenics executed by Jellinger as the morphologist, Riederer and for some time Reynolds as the biochemists and myself as the psychiatric clinician. It is a post mortem study on Spiroperidolbinding in brain tissue of patients who in most cases died after a long stay in a psychiatric hospital. I stress these 3 disciplines we are representatives of and the special design of a post mortem study because these facts both lead to the problem of case definition and -identification and at the same time point out preconditions of such kind of studies which perhaps influence its results. I would like to mention only 2 points depending on the design which are related closely to the topic of my communication.


Time Criterion Psychiatric Hospital Mental Hospital Psychiatric Clinician Neuroleptic Treatment 
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  1. ICD 9th Rev., 1978, “Mental disorders: Glossary and Guide to their Classification in accordance with the 9th Revision of the International Classification of Diseases”, WHO, Geneva.Google Scholar
  2. Reynolds, G., Riederer, P., Jellinger, K., and Gabriel, E., 1981, Dopamine Receptors and Schizophrenia: the neuroleptic drug problem, Neuropharmacology, 20:1319–1320PubMedGoogle Scholar
  3. WPA Diagnostic Criteria, 1983, AmericarTTsychiatric Press, Washington.Google Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Eberhard Gabriel
    • 1
  1. 1.Medical DirectionPsychiatric HospitalA-ViennaAustria

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