Naloxone in the treatment of Anorexia Nervosa: Metabolic and other Effects

  • Ivor H. Mills
  • Linda Medlicott


Anorexia nervosa is a compulsive behaviour disease and is one of a number of such compulsive behaviour diseases. The reasons which brought us to this conclusion are as follows:
  1. (1)

    A number of young ladies are somewhat overweight prior to the development of anorexia nervosa. They often start dieting in a gentle way and succeed in losing weight slowly, with no effect on their menstrual periods. After a period of gradual weight loss they find that, as they say, “suddenly the diet took over”. By this they mean that something inside them drives them to more severe weight loss with severe dieting. Usually from the moment of this change they stop menstruating. During this time they find they have very little ability to control their eating by their own intelligence.



Anorexia Nervosa Compulsive Behaviour Young Lady Severe Weight Loss Gradual Weight Loss 
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  1. Drago, F., Van Ree, J. M., Bohus, B., and De Wied, D., 1981, Endogenous hyperprolactinaemia enhances amphetamine- and apomorphine-induced stereotypy, Eur. J. Pharm., 72:249.CrossRefGoogle Scholar
  2. Medlicott, L., and Mills, I. H., 1983, In preparation.Google Scholar
  3. Mills, I. H., Wilson, R. J., Eden, M. A. M., and Lines, J. G., 1973, Endocrine and social factors in self-starvation amenorrhea, in: “Symposium — Anorexia Nervosa and Obesity,” R. F. Robertson, ed., Royal College of Physicians of Edinburgh, Edinburgh.Google Scholar
  4. Moore, R., Mills, I. H., and Forster, A., 1981, Naloxone in the treatment of anorexia nervosa: effect on weight gain and lipolysis, J. Roy. Soc. Med., 74:129.Google Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Ivor H. Mills
    • 1
  • Linda Medlicott
    • 1
  1. 1.Department of MedicineUniversity of Cambridge Addenbrooke’s HospitalCambridgeEngland

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