Cell Surface Thiols, Methylation, and Complement-Like Components are Involved in the Early Events of CML Whereas Proteases Participate in the Later, Ca++-Dependent Events
The long term goals of our work are to define the chemical and metabolic functions required for cell-mediated lysis, to identify the molecules that participate in the lytic process, and ultimately, to characterize how the molecules mediate the required functions. We have used both murine cytotoxic T lymphocytes (CTL) and human natural killer (NK) cells as model systems. The data to be summarized here were obtained principally with the murine CTL system.
KeywordsProtease Substrate Tyrosine Methyl Ester Tyrosine Methyl Ester Tyrosine Ethyl Ester Human Natural Killer Activity
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