IgE-Dependent Platelet Cytotoxicity Against Helminths
During the last decade, a growing interest has been devoted to parasite immunology, and, more precisely, to the analysis of effector mechanisms against helminths. These works have led to entirely new concepts in cellular immunology, among which the promotion of the eosinophils to the full status of cytotoxic effectors toward several species of trematodes and nematodes, or the description of receptors for IgE on cells other than mast cells and basophils, such as lymphocytes, eosinophils, macrophages and monocytes, the interaction of IgE with its specific receptor on the cell membrane being associated, in most cases, with highly efficient activation processes.
KeywordsSchistosoma Mansoni Normal Platelet Cytotoxic Effector SChistosome Antigen Cytotoxic Process
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