Photochemotherapy of Skin Diseases

  • J. A. Parrish
  • R. S. Stern
  • M. A. Pathak
  • T. B. Fitzpatrick
Part of the Photobiology book series (PB)


While phototherapy is defined as the application of visible or ultraviolet (UV) radiation to the treatment of disease, in photochemotherapy a chemical sensitizer is administered concurrently and the therapeutic effect depends on photochemical interaction of the chemical and radiation. In the doses used, chemical and radiation alone usually have little or no therapeutic effect. Photochemotherapy utilizing psoralen compounds, including 8-methoxy-psoralen, and long-wave UV radiation is currently used in the treatment of many common skin diseases. Other forms of photochemotherapy not utilizing psoralens have been used in the treatment of certain tumors (see Chapter 23). Topical forms of photochemotherapy have been proposed for treatment of recurrent herpes simplex (see Chapters 19–21).


Mycosis Fungoides Bullous Pemphigoid Acta Derm Urticaria Pigmentosa Monofunctional Adduct 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • J. A. Parrish
    • 1
  • R. S. Stern
    • 2
  • M. A. Pathak
    • 1
  • T. B. Fitzpatrick
    • 1
  1. 1.Department of Dermatology, Harvard Medical SchoolMassachusetts General HospitalBostonUSA
  2. 2.Department of Dermatology, Harvard Medical SchoolBeth Israel HospitalBostonUSA

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