Search for Carcinogenic Principles

  • Julia F. Morton
Part of the Recent Advances in Phytochemistry book series (RAPT, volume 14)


Worldwide, large-scale screening of plants for antitumor activity has been in progress for many years. The testing of plants for carcinogenic or cocarcinogenic factors proceeds at a lesser rate because it is the preoccupation of a relatively few investigators. Since plants or plant products, crude or processed, form a major portion of human and animal intake for dietary, recreational or medical purposes, the evaluation of plants so consumed for carcinogenic principles should receive high priority. Of the total cancer deaths occurring annually in England and Wales, 32% (approximately 40,000) are the result of tumors in the esophagus, stomach, pancreas or large bowel.12 Esophageal cancer shows the most striking geographical variation in the incidence of all cancers. This fact, together with the high mortality rate, or usual short-term survival rate, has aroused widespread interest in causation. From my field surveys, observations and research over a 15-year period in a search for possible causes of esophageal cancer, there have evolved inescapable correlations between this disease and high intakes of condensed catechin tannins and related anthocyanins through plant materials deliberately ingested or entering the system via occupational or other exposures.


Esophageal Cancer Cheek Pouch Folk Remedy Geal Cancer Tannin Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Julia F. Morton
    • 1
  1. 1.Morton CollectaneaUniversity of MiamiCoral GablesUSA

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