Metabolic Effects of Psychoactive Drugs

  • D. V. Siva Sankar
  • Eleanor Gold
  • D. Barbara Sankar


The advent and widespread use of psychotomimetic and psychotherapeutic drugs, while of indisputable value, pose certain questions as to their effects on several somatic and metabolic functions—growth in children, resistance to infection, production of antibodies, etc. Furthermore, there is a great need for investigations aimed toward an elucidation of the action of these drugs at the biochemical, cellular, and molecular levels. With this in view, we have attempted to study the metabolic effects of some psychoactive drugs. We have previously reported [1] the metabolic effects of lysergic acid diethylamide (LSD). In the present study, results of the administration of 2-bromolysergic acid analogue (BOL), phenylisopropyl hydrazine (JB 516 or Catron), and chlorpromazine are presented.


Metabolic Effect Psychoactive Drug Urinary Creatinine Hydroxyindole Acetic Acid Keto Acid 
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Copyright information

© Plenum Press Inc. 1962

Authors and Affiliations

  • D. V. Siva Sankar
  • Eleanor Gold
  • D. Barbara Sankar

There are no affiliations available

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