Affective Change in Thyrotoxicosis and Experimental Hypermetabolism

  • W. P. Wilson
  • J. E. Johnson
  • R. B. Smith
  • Roland P. Mackay


Since the hyperthyroid patient may present himself with psychiatric symptomatology, many investigators have concerned themselves with the psychiatric findings in these patients. A review of the literature[1–15] allows one to construct the natural history of the psychiatric symptoms. Typically, the disease may be precipitated by an emotionally significant event. This is frequently followed by a period in which only symptoms of a psychiatric order may occur. After weeks, months, or even one to two years, the physical signs of the disease will become overt. With the onset of these physical findings, the emotional instability may be intensified, according to some investigations. This instability is apparently manifest by symptoms which are related to disturbances in affect since frequent mention is made in the literature of the high incidence of melancholia and mania. After treatment, although the psychiatric symptoms may be reduced in intensity, the patient may continue to show personality disturbances.


Psychiatric Symptom Affective Symptom Hyperthyroid Patient Emotional Instability Affective Change 
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Copyright information

© Plenum Press Inc. 1962

Authors and Affiliations

  • W. P. Wilson
  • J. E. Johnson
  • R. B. Smith
  • Roland P. Mackay

There are no affiliations available

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