Sensitivity Analysis of Errors Induced in the Determination of Tissue Perfusion

  • Avraham Shitzer
  • Robert C. Eberhart


One of the important tasks in physiology and medicine is estimating tissue blood perfusion rate and heat generation rate due to metabolism and other sources. This information is required for experimental studies as well as for clinical purposes and has been the subject of numerous ingenious efforts. The difficulties in performing these measurements are mainly due to (1) the complex anatomical structure of the tissue and interwoven blood supply network of vessels of various sizes and (2) the lack of noninvasive techniques that are capable of directly measuring these quantities. As a result, indirect methods have been devised in which the required information is inferred from measurements of related physical and physiological parameters. Due to these difficulties, the time and spatial resolution of the estimated parameters is compromised and one must accept lower accuracy and precision with these methods.


Effective Thermal Conductivity Tissue Perfusion Blood Perfusion Sensitivity Coefficient Tissue Blood Flow 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Avraham Shitzer
    • 1
  • Robert C. Eberhart
    • 2
  1. 1.Department of Mechanical EngineeringTechnion, Israel Institute of TechnologyHaifaIsrael
  2. 2.Department of SurgeryUniversity of Texas Health Science CenterDallasUSA

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