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A Note on Some Examples of Chiral High-Performance Liquid Chromatographic Resolution in the Pharmaceutical Industry

  • R. J. Collicott
Part of the Chromatographic Society Symposium Series book series (CSSS)

Abstract

Examples of the methods by which enantiomers may be resolved chromatographically using either preliminary derivatisation with a chiral reagent, direct separation using a chiral mobile phase, or by direct separation using a chiral stationary phase (CSP) are outlined. These methods are illustrated by reference to chiral resolutions of compounds of interest to Glaxo Group Research Limited.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • R. J. Collicott
    • 1
  1. 1.Glaxo Group Research LimitedGreenford, MiddlesexUK

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