A Note on Some Examples of Chiral High-Performance Liquid Chromatographic Resolution in the Pharmaceutical Industry

  • R. J. Collicott
Part of the Chromatographic Society Symposium Series book series (CSSS)


Examples of the methods by which enantiomers may be resolved chromatographically using either preliminary derivatisation with a chiral reagent, direct separation using a chiral mobile phase, or by direct separation using a chiral stationary phase (CSP) are outlined. These methods are illustrated by reference to chiral resolutions of compounds of interest to Glaxo Group Research Limited.


Chiral Stationary Phase Chromatographic Resolution Ammonium Dihydrogen Ammonium Dihydrogen Phosphate Chiral Resolution 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • R. J. Collicott
    • 1
  1. 1.Glaxo Group Research LimitedGreenford, MiddlesexUK

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