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Chiral Separations by Thin-Layer Chromatography

  • I. D. Wilson
  • T. D. Spurway
  • L. Witherow
  • R. J. Ruane
  • K. Longden
Part of the Chromatographic Society Symposium Series book series (CSSS)

Summary

Recent progress in thin-layer chromatography (TLC) as a means for the separation of enantiomers is reviewed. The areas discussed include separations using ligand exchange, ion-pair, cyclodextrin and “Pirkle”-based chiral TLC systems. The use of these systems for the chromatographic separation of a variety of enantiomers is described and the robustness, reliability and problems associated with each of these methods considered.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • I. D. Wilson
    • 1
    • 2
  • T. D. Spurway
    • 1
    • 2
  • L. Witherow
    • 1
    • 2
  • R. J. Ruane
    • 1
    • 2
  • K. Longden
    • 1
    • 2
  1. 1.ICI PharmaceuticalsMacclesfield, CheshireUK
  2. 2.V.A. Howe LtdBanbury OxfordshireUK

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