High-Performance Thin-Layer Chromatography: A Quantitative Technique for Enantiomer Separation
Chiral stationary phases for thin-layer chromatography (TLC)/high-performance thin-layer chromatography (HPTLC) are a recent development compared to high-performance liquid chromatography (HPLC). Here the advantages offered by enantiomer resolution in TLC are described and the progress made in quantitative separations reviewed. Using test compounds, sensitivity levels and the possibility of quantitative determinations are investigated for N-(3,5-dinitrobenzoyl)-R-(-)-α-phenylglycine derivatised propylamino silica gel layers.
KeywordsChiral Selector Chiral Stationary Phasis Enantiomer Separation HPTLC Plate Quantitative Separation
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