A Note on a Regulatory View of the Importance of Chiral Discrimination

  • J. W. Bridges
Part of the Chromatographic Society Symposium Series book series (CSSS)


Many of the pesticides, human and veterinary drugs and industrial chemicals in current use incorporate one or more chiral centres. The vast majority of these compounds are marketed as racemates. In most cases no information is available regarding the biological properties of the individual isomers. It is timely to review whether or not this is acceptable for two reasons: (1) there are now many well substantiated cases in which one isomer differs markedly in biological potency from the other and (2) advances in analytical techniques now permit the separate analysis of individual isomers.


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • J. W. Bridges
    • 1
  1. 1.Robens Institute of Health and SafetyUniversity of SurreyGuildford, SurreyUK

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