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Effects of Intravenous Infusion of Urographic Contrast Agents on Glomerular Filtration Rate, Serum Concentration and Urinary Excretion of Uric Acid in Subjects with Normal Renal Function

  • C. Jacobs
  • D. Nicolay
  • J. Grellet
  • Ph. Curet
  • A. Jardin
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 212)

Abstract

The utilization of modern triiodinated radiocontrast agents for intravenous urography (IVU) is widely considered as a very safe procedure in patients free of currently well defined risk factors, amongst which the prominent ones are preexisting renal disease and diabetes mellitus complicated by deteriorated renal function (1,2,3). Whereas the incidence of nephrotoxicity accidents is extremely low in patients with no preexisting renal insufficiency, the risk of an acute, and sometimes definitive, deterioration of renal function following administration of radiocontrast agents has been evaluated as high as 90 % in insulin dependent diabetic patients with severe preexisting renal impairment (1).

Keywords

Uric Acid Serum Uric Acid Normal Renal Function Intravenous Urography Serum Uric Acid Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • C. Jacobs
    • 1
  • D. Nicolay
    • 1
  • J. Grellet
    • 1
  • Ph. Curet
    • 1
  • A. Jardin
    • 1
  1. 1.Hôspital de La Pitiè 83Boulevard de l’HôspitalParisFrance

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