Electrophysiological Application of the Living Extracorporeal Bovine Eye
Seaman and others (1965; 1969; Lutcher et al., 1969) have developed an experimental preparation, “The Living Extracorporeal Bovine Eye”, for direct observation of intravascular coagulation phenomena. In this article, metabolic activity of the extracorporeal eye during perfusion was proved by demonstrating oxygen utilization, carbon dioxide elaboration, and glucose consumption while these activities were abolished by cyanide. If this preparation could be maintained for long periods, it would be of great advantage in many types of investigation, and below we describe modifications of Seaman’s method directed to that end.
KeywordsGlucose Consumption Oscillatory Potential Experimental Preparation Gravity Feed Extracorporeal Perfusion
Unable to display preview. Download preview PDF.
- AMES, A. III. 1965. Biochemistry of the Retina. Suppl. Experimental Eye Res., pp. 22, Academic Press, London.Google Scholar
- SEAMAN, A.J., D.R. RULLMAN, C.L. LUTCHER and C. MOFFAT. 1965. Scand. J. Clin. & Lab. Invest. Suppl. 84, 17.Google Scholar
- SEAMAN, A.J., C.L. LUTCHER and C. MOFFAT. 1969. Blood, 33, 13.Google Scholar
- SICKEL, W. 1966. Clinical Electrophysiology, Proc. Third International Symposium, pp. 115, Pergamon Press, Oxford.Google Scholar
- WEINSTEIN, G.W., M.L. WOLBARSHT and J.E. DOWLING. 1968. Invest. Ophthal., 7, 232.Google Scholar