The Chemical Plasticity of the Brain: The Role of Messenger RNA and Polysomes in Neural Function

  • Stanley H. Appel


The recent advances in molecular biology have begun to reveal the diverse control processes which allow translation of the genetic potential into specific enzyme activities. They demonstrate that these processes and their resultant enzymatic expression depend critically upon interactions of the cell with its environment [1]. Within the nervous system it is clear that perhaps similar and even more sophisticated control mechanisms operate to regulate intercellular and intracellular communication. Both RNA and protein macromolecules may mediate such processes in bacteria, and it is of interest that they may be altered in a variety of experimental situations in brain. However, in brain it is not clear how such changes are brought about and what functions they may serve.


Magnesium Pemoline Radioactive Amino Acid Carbon Platinum Radioactive Leucine Chemical Plasticity 
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© Plenum Press 1967

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  • Stanley H. Appel

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