The Pathogenesis of Intravascular Infection

  • Lawrence R. Freedman
Part of the Current Topics in Infectious Disease book series (CTID)


Intravascular infection is the name applied to microbial proliferation within a platelet-fibrin vegetation located within the circulatory system. The initiation of such an infection depends, in all likelihood, upon the prior establishment of a susceptible, nonbacterial thrombotic vegetation (NBTV) and dissemination via the bloodstream of microorganisms of a sort, and in a number sufficient, to attach to and multiply within the interstices of the vegetation. This sequence of events was well established 50 years ago.(1)


Immune Complex Infective Endocarditis Disseminate Intravascular Coagulation Mycotic Aneurism Bacterial Endocarditis 
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Copyright information

© Plenum Publishing Corporation 1982

Authors and Affiliations

  • Lawrence R. Freedman
    • 1
  1. 1.VA Wadsworth Medical CenterUCLA School of MedicineLos AngelesUSA

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