A New Experimental Model of Sinus Vein Thrombosis

  • M. Deckert
  • K. Frerichs
  • P. Mehraein
  • O. Kempski
  • A. Baethmann
  • K. Einhäupl


Several experimental attempts have failed to induce thrombosis of the cerebral sinus using methods such as ligation, coagulation, or injection of thrombogenic material [1–3]. Ligation and injection of lard-oil or cyanoacrylate into the superior sagittal sinus (SSS) produced obstruction of the SSS, or of the superior cerebral veins (SCV) yet without evidence of thrombosis [4–7]. Materials such as scandium chloride, sodium morrhuate, or thrombin injected into the SSS may cause sinus or vein thrombosis. However, histological changes of the brain were either absent or not systematically investigated [8–10].


Brain Edema Superior Sagittal Sinus Cortical Vein Thrombosis Sagittal Sinus Thrombosis Ischemic Nerve Cell Damage 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • M. Deckert
    • 1
  • K. Frerichs
    • 2
  • P. Mehraein
    • 3
  • O. Kempski
    • 2
  • A. Baethmann
    • 2
  • K. Einhäupl
    • 1
  1. 1.Department of NeurologyLudwig-Maximilians-University, Klinikum GroßhadernMunich 70Germany
  2. 2.Institute of Surgical ResearchLudwig-Maximilians-University, Klinikum GroßhadernMunich 70Germany
  3. 3.Department of NeuropathologyLudwig-Maximilians-University, Klinikum GroßhadernMunich 70Germany

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