Perinatal Changes in Hemoglobin Concentration in Rats

  • F. L. Ubels
  • W. P. Meeuwsen
  • S. Wijkstra
  • B. Oeseburg
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 277)


During experiments on oxygen availability in fetal rats using pulse oximetry as presented by Wijkstra et al.(1989), we were struck by the low total hemoglobin concentration (cHb) in the fetal blood. Since hemoglobin serves as the main oxygen carrier, the course of cHb during fetal life should be investigated before using the rat as an animal model in oxygen transport research.


Hemoglobin Concentration Sodium Nitrite Fetal Blood Mean Corpuscular Hemoglobin Concentration Corpuscular Hemoglobin Concentration 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • F. L. Ubels
    • 1
  • W. P. Meeuwsen
    • 1
  • S. Wijkstra
    • 1
  • B. Oeseburg
    • 2
  1. 1.Dept. of PhysiologyUniversity of GroningenThe Netherlands
  2. 2.Dept. of PhysiologyUniversity of NijmegenThe Netherlands

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