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Distribution of Ventilation and Diffusion with Perfusion in a Two-Compartment Model of Gas Exchange

  • M. F. Vidal Melo
  • A. Caprihan
  • U. C. Luft
  • J. A. Loeppky
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 277)

Abstract

Since the 1940’s mathematical models have been applied to the study of gas exchange (Riley and Cournand, 1949). This is because it is possible to describe the lung, in respiratory physiology, as a set of units with qualitatively similar mathematical description, which can be added for an overall result. As chemical processes are involved in the relationships between gas partial pressures and contents in the blood, such a description involves the solution of non-linear, interdependent and differential equations. Due to the difficulties of such calculations at those early times, most of the work was restricted to graphical analyses with several simplifying assumptions.

Keywords

Dissociation Curve Alveolar Ventilation Bohr Effect Perfusion Ratio Partial Pressure Difference 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • M. F. Vidal Melo
    • 1
    • 2
  • A. Caprihan
    • 1
    • 2
  • U. C. Luft
    • 1
    • 2
  • J. A. Loeppky
    • 1
    • 2
  1. 1.Lovelace Medical FoundationAlbuquerqueUSA
  2. 2.Abteilung für Experimentelle ChirurgieHeidelberg 1Germany

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