Myocardial Oxygen Supply in Coronary Artery Disease

  • M. Thomas
  • J. Grote
  • J. Nitsch
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 277)


It is generally accepted that adaptation of coronary blood flow to exercise is limited in coronary artery disease. However, there are still controversial discussions whether coronary blood flow and myocardial metabolism are restricted under resting conditions in these patients (Opie, 1968, 1969; Ganz et al., 1971; Klocke et al., 1974; Mymin and Sharma, 1974; Braunwald and Sobel, 1988; Thomassen et al., 1988). To investigate the behavior of myocardial blood flow and metabolism as well as the efficiency of left ventricular work in coronary artery disease, measurements were performed in patients during cardiac catheterization.


Myocardial Blood Flow Coronary Sinus Mean Arterial Blood Pressure Coronary Blood Flow Coronary Artery Disease Patient 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • M. Thomas
    • 1
  • J. Grote
    • 1
  • J. Nitsch
    • 2
  1. 1.Department of PhysiologyUniversity of BonnBonnGermany
  2. 2.Department of CardiologyUniversity of BonnBonnGermany

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