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Response Time of Mitochondrial Oxygen Consumption Following Stepwise Changes in Cardiac Energy Demand

  • J. H. G. M. van Beek
  • N. Westerhof
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 277)

Abstract

When the metabolic demand of the heart changes, the mitochondria alter their ATP-production which is linked to mitochondrial oxygen consumption. The control mechanisms of mitochondrial respiratory rate are under debate (Chance et al., 1986; Katz et al., 1989; Erecinska and Wilson, 1982). Knowledge of the time course of mitochondrial oxygen consumption following changes in ATP-hydrolysis could give important information on mitochondrial metabolic control mechanisms and adaptation to cellular energy demand.

Keywords

Oxygen Uptake Rabbit Heart Perfusion Flow Stepwise Change Tyrode Solution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • J. H. G. M. van Beek
    • 1
  • N. Westerhof
    • 1
  1. 1.Laboratory for PhysiologyFree UniversityAmsterdamThe Netherlands

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