Fine Structure of Capillary Proliferation in Myocardium of Volume Overloaded Rats
Ultrastructural changes of the capillary in the myocardium of the volume over-loaded hearts are not well understood. Recently we have shown that endothelial ceU proliferation is observed in the flow loaded canine and rat carotid arteries (Masuda et al., 1985; Tohda et al., 1988). We suppose that the endothelial ceU will respond to the flow change in the capillaries of the myocardium of the volume-loaded hearts, because flow is expected to be increased in them. In this report, we describe ultrastructural changes of the capiUaries of the left ventricle myocardium of volume-loaded rat hearts, produced by arterio-venous shunt (A-V shunt) between the common carotid artery and the external jugular vein.
KeywordsWall Shear Stress Common Carotid Artery Coronary Blood Flow Blood Flow Rate Intercellular Junction
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- Carlsson, S., A. Ljungqvist, G. Tornling and G. Unge, 1978, The myocardial capillary vasculature in repeated physical exercise, Acta Path. Microbiol. Scand. Sect. A., 86: 117–119.Google Scholar
- Ljungqvist, A., G. Unge and S. Carlsson, 1976, The myocardial capillary vasculature in exercising animals with increased cardiac pressure load, Acta Path. Microbiol. Scand. Sect. A, 84: 244–246.Google Scholar
- Tohda, K., H. Masuda, K. Kawamura and T. Shozawa, 1988, Ultrastructural changes in the endothelial surface of rat carotid artery induced by blood flow load — a scanning electron microscopical study, in “Role of blood flow in atherogenesis”, Y. Yoshida et al., eds., Springer-Verlag, Tokyo, 171–177.CrossRefGoogle Scholar
- Tornling, G., 1982, Capillary neoformation in the heart of dipyridamole-treated rats, Acta Path. Microbiol. Immunol. Scand. Sect. A., 90: 269–271.Google Scholar