Perfluorochemical Oxygen Carriers and Ischaemic Tissues

  • Kenneth C. Lowe
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 277)


There is growing interest in the potential use of synthetic, oxygen-carrying perfusates for the management of hypoxically ischaeraic tissues. One such approach is to use perfusates based on emulsified perfluorochemicals (PFCs) and this has received much attention in recent years. This paper considers progress in this area and evaluates the potential beneficial therapeutic value of emulsified PFCs in myocardial, cerebral and intestinal ischaeraia. Recent advances in the development and assessment of improved PFC emulsions have also been highlighted.


Middle Cerebral Artery Occlusion Focal Cerebral Ischemia Blood Substitute Ischaemic Tissue Percutaneous Trans Luminal Coronary Angioplasty 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Kenneth C. Lowe
    • 1
  1. 1.Mammalian Physiology Unit, Dept. ZoologyUniversity of NottinghamNottinghamUK

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