Concentric Oxygen Diffusion in Tissue with Heterogeneous Permeability and Consumption

  • Louis Hoofd
  • Zdenek Turek
  • Stuart Egginton
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 277)


Most modelling of oxygen diffusion in tissue has considered the properties of the tissue to be homogeneous, not dependening on location. However, in tissue different portions can be discerned, resulting in heterogeneity with respect to oxygen diffusion and consumption. Such tissue heterogeneity was considered in a concentric diffusion model (Rakusan et al. , 1984) , the oxygen diffusing inward into a circular region consisting of two zones: a central one and a ring-shaped outer one, each having different oxygen consumptions. Capillaries were located at the outer border of the circular region, regularly spaced and all having the same capillary radius and oxygen pressure, while oxygen permeability had to be the same in both zones.


Oxygen Partial Pressure Capillary Pressure Oxygen Pressure Oxygen Diffusion Oxygen Transport 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Louis Hoofd
    • 1
  • Zdenek Turek
    • 1
  • Stuart Egginton
    • 2
  1. 1.Dept. PhysiologyUniversity of NijmegenNijmegenThe Netherlands
  2. 2.Dept. Physiology, Medical SchoolThe University of BirminghamBirminghamUK

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