A Method for Measuring the Rate of Oxygen Release from Flowing Erythrocytes in Microvessels

  • N. Tateishi
  • N. Maeda
  • T. Shiga
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 277)


Physiologically, dynamics of oxygen release from erythrocytes in capillary to tissues is one of the most important phenomena. The major determinants of oxygen supply to tissues are blood flow to tissues, oxygen content in blood and the density of capillaries. The importance of capillary density has been well examined since the pioneering study of Krogh1.


Oxygen Saturation Oxygen Release Venous Side Hamster Cheek Pouch Arterial Side 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    A. Krogh, The number and distribution of capillaries in muscles with calculations of the oxygen pressure head necessary for supplying the tissue, J. Physiol. Lond. 52:409–415 (1919).PubMedGoogle Scholar
  2. 2.
    T. Shiga, N. Maeda and N. Tateishi, Kinetics of blood cell aggregation by video-image processing, in: “Microcirculation an Update”, Vol.1, M. Tsuchiya, M. Asano, Y. Mishima, and M. Oda, ed., pp.433–436, Elsevier, Amsterdam (1987).Google Scholar
  3. 3.
    N. Tateishi, N. Maeda and T. Shiga, A new method for spectral analysis of flowing blood in microvessel, in: “Microcirculation Annual 1988”, M. Tsuchiya, M. Asano and S. Matsuyama, ed., pp.121–122, Nihon-igakukan, Tokyo (1989).Google Scholar
  4. 4.
    O. W. Van Assendelft, “Spectrophotometry of Haemoblobin Derivatives.” Royal VanGorcum. Assen, The Netherland (1970).Google Scholar
  5. 5.
    R. N. Pittman, and B. R. Duling, A new method for the measurement of percent oxyhemoglobin, J. Appl. Physiol. 38:315–320 (1975).PubMedGoogle Scholar
  6. 6.
    B. R. Duling, D. N. Damon, S. R. Donaldson, and R. N. Pittman, A computerized system for densitometric analysis of the microcirculation, J.Appl. Physiol., 55:642–651 (1983).PubMedGoogle Scholar
  7. 7.
    R. L. Hester, and B. R. Duling, Red cell velocity during functional hyperemia: implications for rheology and oxygen transport, Am. J. Physiol., 255:H236-H244 (1988).PubMedGoogle Scholar
  8. 8.
    H. Wayland, and P. C. Johnson, Erythrocyte velocity measurement in microvessels by a two slit photometric method, J. Appl. Physiol., 22:333–337 (1967).PubMedGoogle Scholar
  9. 9.
    M. Intaglietta, N. R. Silverman, and W. R. Tompkins, Capillary flow velocity measurements in vivo and in situ by television methods, Microvasc. Res., 10:165–179 (1975)PubMedCrossRefGoogle Scholar
  10. 10.
    D. P. Swain, and R. N. Pittman, Oxygen exchange in the microcirculation of hamster retractor muscle, Am. J. Physiol., 256:H247-H255 (1989).PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • N. Tateishi
    • 1
  • N. Maeda
    • 1
  • T. Shiga
    • 2
  1. 1.Department Physiology, School of MedicineEhime UniversityShigenobu, Onsen-gun, EhimeJapan
  2. 2.Department Physiology, School of MedicineOsaka UniversityNakanoshima, Kita-ku, Osaka 530Japan

Personalised recommendations