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Membrane Potential of Squid Axons

  • Shinpei Ohki

Abstract

The resting membrane potentials of squid axons were meassured as a function of the nature of the ionic species as well as the ionic strength of the extracellular and intracellular media. The observed membrane potentials were analyzed using two equations: a) the Goldman-Hodgkin-Katz equation, and b) the surface/diffusion potential equation. The overall experimental results were found to be explained better by the surface/diffusion potential equation. The surface charge densities of the outer and inner surfaces (on the surface responsible for the ion transfer) of the squid axons were found to be approximately -e/180 Å2 and -e/1300 Å2, respectively. Using the obtained surface charge densitities and the membrane potential equation involving divalent cations, the relative permeabilities (with respect to K+) of divalent cations across the squid axon membrane were obtained to be 0.033 for Ca2+, 0.031 for Sr2+ and 0.022 for Mg2+ from the experimental data.

Keywords

Membrane Potential Divalent Cation Relative Permeability Surface Charge Density Rest Membrane Potential 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Shinpei Ohki
    • 1
  1. 1.Department of Biophysical Sciences School of MedicineState University of New York at BuffaloBuffaloUSA

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