The Myosin Filament; Charge Amplification and Charge Condensation

  • G. F. Elliott
  • E. M. Bartels
  • R. A. Hughes


Current models for the molecular mechanism of muscular contraction are derived largely from structural and biochemical information. Experimental evidence has traditionally been obtained as answers to questions like “where are the various contractile proteins located, what are the physical and chemical properties of the isolated, purified proteins in solution, how do the kinetics of muscle chemistry correlate with structural changes in working muscles?” A detailed picture of many essential events in muscle contraction has been obtained in this manner and has been incorporated into current views of the sliding filament hypothesis, see for example the monographs of A.F. Huxley (1980) and Bagshaw (1982).


Sarcomere Length Myosin Head Thick Filament Myosin Filament Myosin Molecule 


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • G. F. Elliott
    • 1
  • E. M. Bartels
    • 1
  • R. A. Hughes
    • 1
  1. 1.Oxford Research UnitOpen UniversityBoars Hill, OxfordEngland

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