The Reversibility of Obesity, Diabetes, Hyperlipidemia, and Coronary Heart Disease

  • James W. Anderson
  • Abayomi O. Akanji


The most important cause of death in Western countries is cardiovascular disease. It accounts for about 36% of all deaths in the United States; in 1988, total health spending on prevention and treatment of heart disease was about $84 billion (1,2). The situation is likely similar in the other developed northern European countries. Coronary heart disease (CHD) is easily the most frequent and most important cardiovascular disease in these countries in the second half of the twentieth century, with the eradication of infectious disease and consequent reduction in the prevalence of rheumatic and syphilitic heart disease, and with improved technology for the earlier detection and management of congenital heart disease. This high prevalence of CHD is directly attributable to lifestyle and dietary factors, most of which are modifiable(3). The lifestyle-related risk factors are cigaret smoking, physical inactivity, and poor stress management; the diet-related factors are hyperlipidemia, hypertension, diabetes, and obesity (3). These factors have independent and additive effects not only in the genesis of CHD but also in the pathogenesis of the other factors. As an example, obesity can precipitate noninsulin-dependent diabetes mellitus (NIDDM) in the individual so predisposed; also the diabetic state can worsen atherogenic lipid profiles in individuals already genetically prone to hyperlipidemia.


Coronary Heart Disease Glycemic Control Wheat Bran High Fiber High Carbohydrate 
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Copyright information

© Humana Press, Totowa, NJ 1994

Authors and Affiliations

  • James W. Anderson
  • Abayomi O. Akanji

There are no affiliations available

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