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Coupling of Chemical Reaction to Transport of Sodium and Potassium

  • J. C. Skou
Part of the Nobel Foundation Symposia book series (NOFS, volume 34)

Abstract

The membrane bound (Na++K+)-activated ATP hydrolyzing enzyme system (Na++K+ ATPase in the following) couples the flux of sodium and of potassium along their electrochemical gradients across the cell membrane — sive flux — to a flux of the same ions against their electrochemical gradients — the active transport (see Skou, 1975). The coupling is tight enough to give a steady-state concentration of sodium and of potassium in the cell which is away from thermodynamic equilibrium of the two cations.

Keywords

Electrochemical Gradient Adenosine Triphosphatase Sodium Pump Apparent Affinity Active Flux 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • J. C. Skou
    • 1
  1. 1.Institute of PhysiologyUniversity of AarhusAarhus CDenmark

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