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Recent Findings in the Structural and Functional Aspects of the Peptide Ionophores

  • Yu. A. Ovchinnikov
Part of the Nobel Foundation Symposia book series (NOFS, volume 34)

Abstract

The last decade is witness to the birth and tempestuous development of a new field in bioorganic chemistry. Its objects are membrane—active complex-ones (see [1] and references therein), often called ionophores because of their ability to bind metal ions in solution and carry them along in one or the other stage of the transmembrane ion transporting process. It is this property which has won for the ionophores a secure place in the arsenal of modern biochemical and biophysical techniques as highly effective tools for studying ion movements across membranes.

Keywords

Electron Spin Resonance Spectrum Functional Aspect Dansyl Derivative Picrate Anion Potassium Picrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Yu. A. Ovchinnikov, V. T. Ivanov, A. M. Shkrob, Membrane Active Complexones, Elsevier, Amsterdam, 1974.Google Scholar
  2. 2.
    V. F. Bystrov, Yu. D. Gavrilov, V. T. Ivanov, Yu. A. Ovchinnikov, in preparation.Google Scholar
  3. 3.
    M. Pinkerton, L. K. Steinrauf, P. Dawkins, Biochem. Biophys. Res. Communs, 35, 512 (1969).CrossRefGoogle Scholar
  4. 4.
    K. Neupert—Laves, M. Dobler, Helv. Chim. Acta, 58, 432 (1975).PubMedCrossRefGoogle Scholar
  5. 5.
    G. N. Tischenko, Z. Karimov, B. K. Vainshtein, A. V. Evstratov, V. T. Ivanov, Yu. A. Ovchinnikov. FEBS Letters, in press.Google Scholar
  6. 6.
    Yu. A. Ovchinnikov, V. T. Ivanov, A. V. Evstratov, I. I. Mikhaleva, V. F. Bystrov, S. L. Portnova, T. A. Balashova, E. A. Meshcheryakova, V. M. Tulchinsky, Int. J. Pept. Prot. Res., 6, 465 (1974)CrossRefGoogle Scholar
  7. 7.
    T. G. Shishova, V. I. Simonov, V. T. Ivanov, I. I. Mikhaleva, T. A Balashova, Yu. A. Ovchinnikov, Bioorgan. Chim. (USSR), 1, 1689 (1975).Google Scholar
  8. 8.
    V. T. Ivanov, L. V. Sumskaya, I. I. Mikhaleva, I. A. Laine, I. D. Ryabova, Yu. A. Ovchinnikov, Chim,Prirodn. Soed. (USSR), 346 (1974).Google Scholar
  9. 9.
    L. V. Sumskaya, T. A. Bglashova, T. S. Chumburidze, V. T. Ivanov, Yu. A. Ovchinnikov, Bioorgan. Chim. (USSR), 2 (in press).Google Scholar
  10. 10.
    V. T. Ivanov, A. V. Evstratov, T. A. Balashova, E. A. Meshcheryakova, S. L. Portnova, V. F. Bys-trov, Yu. A. Ovchinnikov, Bioorgan. Chim. (USSR), 2 (in press).Google Scholar
  11. 11.
    I,M. Andreev, G. G. Malenkov, A. M. Shkrob, M. M. Shemyakin, Molec. Biol. (USSR), 5, 614 (1971).Google Scholar
  12. 12.
    L. V. Sumskaya, N. M. Chekhlayeva, L. I. Barsukov, O. P. Terekhov, V. V. Djomin, A. M. Shkrob, V. T. Ivanov, Yu. A. Ovchinnikov, Bioorgan. Chim. (USSR), 2, 351 (1976).Google Scholar
  13. 13.
    V. S. Markin, V. F. Pastushenko, L. I. Krishtalik, E. A. Libernnan, V. P. Topaly, Biophysika (USSR), 14, 462 (1969).Google Scholar
  14. 14.
    W. R. Veatch, R. Mathies, M. Eisenberg, L. Stryer, J. Mol. Biol., 99, 75 (1975).PubMedCrossRefGoogle Scholar
  15. 15.
    M. M. Shemyakin, Yu. A. Ovchinnikov, V. T. Ivanov, V. K. Antonov, E. I. Vinogradova, A. M. Shkrob, G. G. Malenkov, A. V. Evstratov, I. D. Ryabova, I. A. Laine, E. I. Melnik, J. Membr. Biol. 1, 402 (1969).CrossRefGoogle Scholar
  16. 16.
    E. Grell, Th. Funck, F. Eggers, in Membranes (G. Eisenman, ed. ) Marcel Dekker Inc., New-York-Basel, 1975, vol. 3, pp. 2–216Google Scholar
  17. 17.
    V. T. Ivanov, Ann. N. Y. Acad. Sci., 264, 221 (1975).PubMedCrossRefGoogle Scholar
  18. 18.
    V. T. Ivanov, L. A. Fonina, N. N. Uvarova, S. A. Koz’min, T. B. Kropotnitskaya, N. M. Chakh-layeva, T. A. Balashova, V. F. Bystrov, Yu. A. Ovchinnikov, Peptides Chemistry,Strucnture and Biology (R. Waiter, J. Meienhofer, eds. ), Ann. Arbor Sci. Publ., Ann Arbor(1975).Google Scholar
  19. 19.
    V. T. Ivanov, A. V. Evstratov, L. V. Sumskaya, E. I. Melnik, T. S. Chumburidze, S. L. Portnova, T. A. Balashova, Yu. A. Ovchinnikov, FEBS Letters, 36, 65 (1973).CrossRefGoogle Scholar
  20. 20.
    Yu. A,Ovchinnikov, FEBS Letters, 44, 1 (1974).PubMedCrossRefGoogle Scholar
  21. 21.
    D. A. Hayden, S. B. Hladky, Quart. Rev., Biophys., 5, 187 (1972).CrossRefGoogle Scholar
  22. 22.
    W. R. Veatch, E. T. Fossel, E. R. Blout, Biochemistry, 13, 5249 (1974).PubMedCrossRefGoogle Scholar
  23. 23.
    P. W. Urry, M. C. Goodall, J. D. Glickson, D. F. Mayers, Proc. Nat:. Acad, Sci. US, 68, 1907 (1971)CrossRefGoogle Scholar
  24. 24.
    E. T. Fossel, W. R. Veatch, Yu. A. Ovchinnikov, E. R. Blout, Biochemistry, 13, 5264 (1974).PubMedCrossRefGoogle Scholar
  25. 25.
    E. N. Shepel, St. lordanov, I. D. Ryabova, A. I. Miroshnikov, V. T. Ivanov, Yu. A. Ovchinnikov, Bioorgan. Chim. (USSR), 2, 581 (1976).Google Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Yu. A. Ovchinnikov
    • 1
  1. 1.Shemyakin Institute of Bioorganic ChemistryUSSR Academy of SciencesMoscowUSSR

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