X-ray Scattering Studies of Protein-Lipid Systems in Solution: The Example of Bovine Rhodopsin
Small-angle X-ray scattering, one of the most powerful techniques for the study of macromolecules in solution, has been applied to a variety of systems of biological interest. A shortcoming of this technique, especially if compared to a conventional crystallographic approach, is its poor resolution, orders of magnitude short of atomic resolution; its main advantage is the possibility of easily varying physical and chemical conditions and exploring structural transitions. Furthermore, biological systems are not always amenable to high resolution crystallographic analysis.
KeywordsBovine Rhodopsin Partial Specific Volume Detergent Micelle Rhodopsin Molecule Electron Density Fluctuation
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