Advertisement

Molecular Arrangement and Conformation of Lipids of Relevance to Membrane Structure

  • Sixten Abrahamsson
  • Birgitta Dahlén
  • Håkan Löfgren
  • Irmin Pascher
  • Staffan Sundell
Part of the Nobel Foundation Symposia book series (NOFS, volume 34)

Abstract

Intact membranes as well as membrane components have been studied extensively by various physical and chemical methods. Important data have accummulated but more specific structural information on the atomic level is still necessary in order to obtain a detailed understanding of lipid-lipid and lipid-protein interactions and of variations in structure and composition of lipids observed in different types of membranes. Only then will it be possible to explain the function of the different constituents and their significance for various membrane properties.

Keywords

Cholesteryl Ester Hydrocarbon Chain Lipid Layer Sugar Residue Molecular Arrangement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Abrahamsson, S. and Ryçlerstedt-Nahringbauer, I., The crystal structure of the low-melting form of oleic acid, Acta Cryst., 15, 1261, 1962.CrossRefGoogle Scholar
  2. Abrahamsson, S., Ställberg-Stenhagen, S. and Stenhagen, E., The higher saturated branched chain fatty acids, in Progress in the Chemistry of Fats and other Lipids, Vol. 7, 1963.Google Scholar
  3. Abrahamsson, S. and Westerdahl, A., The crystal structure of 3-thiadodecanoic acid, Acta Cryst., 16, 404, 1963.CrossRefGoogle Scholar
  4. Abrahamsson, S. and Pascher, I., Crystal and molecular struc- ture of L-a-glycerylphosphorylcholine, Acta Cryst., 21, 79, 1966.CrossRefGoogle Scholar
  5. Abrahamsson, S., Pascher, I., Larsson, K. and Karlsson, K. -A., Molecular arrangements in glycosphingolipids, Chem. Phys. Lipids 8, 152, 1972.CrossRefGoogle Scholar
  6. Abrahamsson, S. and Dahlén, B., The crystal structure of cholesteryl-17-bromoheptadecanoate, J. C. S. Chem. Comm., 117, 1976 a.Google Scholar
  7. Abrahamsson, S. and Dahlén, B., The crystal structure of cholesteryl-17-bromoheptadecanoate, submitted for publication 1976 b.Google Scholar
  8. Abrahamsson, S., Dahlén, B. and Pascher, I., Molecular arrangements in glycosphingolipids. Crystal structure of glucosylphytosphingosine hydrochloride, Acta Cryst., in press, 1976.Google Scholar
  9. Andrew, E. R., Molecular motion in certain solid hydrocarbons, J. Chem. Phys., 18, 607, 1950.CrossRefGoogle Scholar
  10. Björkman, L.R., Karlsson, K. -A., Pascher, I. and Samuelsson, B. E., The identification of large amounts of cerebroside and cholesterol sulphate in the sea star, asterias rubens, Biochim. Biophys.Acta 270, 260, 1972.Google Scholar
  11. Craven, B. M. and DeTitta, G. T., Cholesteryl myristate: structures of the crystalline solid and mesophases, J. Chem. Soc. Perk II, in press, 1976.Google Scholar
  12. Dahlén, B. and Pascher, I., Molecular arrangements in sphingolipids. Crystal structure of N-tetracosanoylphytosphingosine, Acta Cryst., B28, 2396, 1972.CrossRefGoogle Scholar
  13. Dahlén, B., Lundén, B. -M. and Pascher, I., The crystal structure of 2-DL-hydroxytetradecanoic acid, Acta Cryst., in press, 1976.Google Scholar
  14. Dahlén, B., Pascher, I. and Sundell, S., The crystal structure of N-(2-hydroxyethyl)-octadecanamide, submitted for publication, 1976.Google Scholar
  15. Hakomori, S. -I., Glycolipids of tumor cell membranes, Adv. Can-. cer Res., 18, 265, 1973.Google Scholar
  16. Harkins, W. D., The surface of solids and liquids and the films that form upon them, in Colloid Chemistry, vol. 5, Reinhold Publishing Corp., New York, 1944.Google Scholar
  17. Hayashi, M., Muramatsu, T. and Hara, I., Surface properties of synthetic phospholipids, Biochisn. Biophys. Acta, 255, 98, 1972.CrossRefGoogle Scholar
  18. Hitchcock, P. B., Mason, R., Thomas, K. M. and Shipley, G. G. Structural chemistry of 1, 2-dilauroyl-DL-phosphatidylethanolamine: Molecular conformation and intermolecular packing of phospholipids, Proc. Nat. Acad. Sci. U. S., 71, 3036, 1974.CrossRefGoogle Scholar
  19. Karlsson, K. -A. and Samuelsson, B. E., The structure of ceramide aminoethylphosphonate from the sea anemone, metridium senile, Biochim. Biophys.Acta, 337, 204, 1974.Google Scholar
  20. Löfgren, H. and Pascher, I., Molecular arrangement in sphingolipids. Lateral interaction of ceramides in monolayers, to be published.Google Scholar
  21. Lundén, B. -M., The crystal structure of 12-D-hydroxyoctade- canoic acid methyl ester, Acta Cryst., in press, 1976.Google Scholar
  22. Nilsson, B. and Pascher, I., The crystal and molecular structure of the hydrochloride and hydrobromide of sphingosine. Submitted for publication, 1976.Google Scholar
  23. O’Brien, J. S. and Sampson, E. L., Lipid composition of the normal human brain: grey matter, white matter, and myelin, J. Lipid Res., 6, 537, 1965.PubMedGoogle Scholar
  24. O’Connell, A. M. and Pascher, I., The crystal structure of triacetylsphingosine, Acta Cryst., B25, 2553, 1969.CrossRefGoogle Scholar
  25. Pascher, I., Molecular arrangements in sphingolipids. Conforma- tion and hydrogen bonding of ceramide and their implication on membrane stability and permeability, Biochim. Biophys. Acta, submitted for publication, 1976.Google Scholar
  26. Pascher, I. and Sundell, S., Molecular arrangement of sphingolipids. The crystal structure of a cerebroside: ß-D-galactosyl-N-octadecanoyl-D-dihydrosphingosine, in preparation.Google Scholar
  27. Phillips, M. C. and Chapman, D., Monolayer characteristics of saturated 1, 2-diacylphosphatidylcholine (lecithins) and phosphatidylethanol-amines of the air-water interface, Biochim. Biophys. Acta, 163, 301, 1968.Google Scholar
  28. Segerman, E., The modes of hydrocarbon chain packing, Acta Cryst., 19, 789, 1965.CrossRefGoogle Scholar
  29. Sundaralingam, M., Molecular structures and conformations of the phospholipids and sphingomyelins, Ann. N. Y. Acad. Sci. 195, 324, 1972.PubMedCrossRefGoogle Scholar
  30. Sundell, S., The crystal structure of sodium dodecyl sulphate, to be published, 1976 a.Google Scholar
  31. Sundell, S., The crystal structure of sodium cholesteryl sulphate, to be published, 1976 b.Google Scholar
  32. Svennerholm, L. and Ställberg-Stenhagen, S., Changes in the fatty acid composition of cerebrosides and sulfatides of human nervous tissue with age, J. Lipid Res., 9, 215, 1968.PubMedGoogle Scholar
  33. Wiegandt, H., Glycosphingolipids, Adv. Lipid Res. 9, 249, 1971.Google Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Sixten Abrahamsson
    • 1
  • Birgitta Dahlén
    • 1
  • Håkan Löfgren
    • 1
  • Irmin Pascher
    • 1
  • Staffan Sundell
    • 1
  1. 1.Dept. of Structural Chemistry, Faculty of Medicine,University of GöteborgGöteborg 33Sweden

Personalised recommendations