• Anil K. Mandal
  • Robert C. Muehrcke


A variety of pathological states, e.g., acute interstitial nephritis, chronic interstitial nephritis, and papillary necrosis, involve the renal papilla. Although its existence has been known for several decades (Councilman, 1898), only since 1960 has the renal interstitium constituted an increasingly important subject for discussion among clinicians. This interest has been warranted in part by the frequent use of drugs such a methicillin in combating staphylococcal infections, often leading to an undesirable reaction affecting the renal interstitum—acute interstitial nephritis.


Interstitial Cell Interstitial Nephritis Renal Medulla Vasoactive Substance Acute Interstitial Nephritis 


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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • Anil K. Mandal
    • 1
  • Robert C. Muehrcke
    • 2
  1. 1.Department of MedicineVeterans Administration Medical Center and University of Oklahoma College of MedicineOklahoma CityUSA
  2. 2.Department of MedicineWest Suburban HospitalOak ParkUSA

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