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Specificity of Myelin Basic Proteins

  • Marian W. Kies

Abstract

A number of studies have appeared in the last ten years on the isolation from central nervous system (CNS) of certain highly basic proteins which are capable of inducing experimental allergic encephalomyelitis (EAE).(1–10) These studies have depended largely on tests of biological activity to monitor the fractionation procedures. Such tests are still an important part of our investigative procedures, even though the myelin basic proteins(2) are probably the best characterized of the proteins isolated from the CNS. They have been isolated from many species, and the amino acid compositions of several have been reported.(7–13) Considerable information is also available regarding amino acid sequence of certain parts of the molecule.(8,14)

Keywords

Myelin Basic Protein Basic Protein Experimental Allergic Encephalomyelitis Minimum Molecular Weight Bovine Myelin Basic Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • Marian W. Kies
    • 1
  1. 1.Section on Myelin Chemistry Laboratory of Cerebral MetabolismNational Institute of Mental HealthBethesdaUSA

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