Fast Axoplasmic Transport of Proteins and Polypeptides in Mammalian Nerve Fibers
Using isotopic labeling techniques, it has been verified that in nerve there is a transport system constantly moving materials from the soma out into the axons and likely also into the post-synaptic cell. (1–3) The modern view of neuron is that it is a cell with a high level of protein synthesis,(4)and the preponderance of evidence discussed in the above reviews indicates that most of the synthesis takes place in the soma, where a high level of RNA is present in the ribosomes of the Nissl bodies. Some studies, however, indicate that synthesis is possible in other parts of the cell (see below and Austin and Morgan(5)).
KeywordsSciatic Nerve Fast Component Ventral Root Motor Fiber Fast Transport
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